Ohio State then-sophomore attack Tre Leclaire walks off the field with his teammates after scoring his first goal of the game in the first quarter against Michigan on April 13, 2018. Ohio State beat the Wolverines 8-5. Credit: Edward Sutelan | Editor In ChiefOhio State found scoring from seven different players against Boston University on Saturday, but it also relied on the same players from the week before.In the Buckeyes’ 17-10 win against the Terriers, senior midfielder Jack Jasinski and junior attacker Tre LeClaire came up big once again, giving Ohio State nine goals between the two.Jasinski’s five goals were a team high and LeClaire added four of his own to give the pair eight and seven goals on the season, respectively.“The goal every year is to improve,” Jasinski said. “This year I keep chipping away and at it and luckily the results came our way.”Ohio State (2-0) and its’ fast-paced offense came out with a 10-3 lead at the half, before senior attacker James Burr and Boston (1-1) made a surge comeback in the second half to close the gap before the Buckeyes ultimately pulled away late for a seven-goal win.“You take confidence from doing, and we were confident going into today from what we saw in practice this week,” head coach Nick Myers said. “I think the guys were confident that all we needed to do was do what we did for three or four days that to me was probably the biggest key, we didn’t have that feeling a week ago, and I love the way the guys responded to last week.”The offense was on full display from the start of the whistle, with Jasinski opening the scoring with a goal less than a minute into the contest. Boston countered that with a goal early from freshman attacker Timmy Ley, but the Buckeyes would get three straight goals for a 4-1 lead.The Terriers would get another goal before Ohio State came back again with three straight goals to end the first quarter with a 7-2 lead. The second quarter was more of the same, with the Buckeyes starting the quarter off quickly on a goal by sophomore midfielder Colby Barker, his first goal of the season, helping Ohio State take a seven-goal lead into a halftimeIn the third quarter, the game started to turn. after the third goal from LeClaire, Boston scored four straight goals to cut the game to 11-7 before the Buckeyes ended the quarter with back-to-back goals for a 13-8 lead heading into the fourth quarter.Ohio State outscored the Terriers 4-3 in the final frame to take the victory and move to 2-0 on the season“We were trying to do a little too much, and we got back to it in the fourth quarter,” Jasinski said.Burr finished with six goals for the Terriers, and Boston freshman goalie Joe McSorley made five saves on 22 attempts.Ohio State freshman goalie Skylar Wahlund made his first career start, making eight saves and leaving the game with a .500 save percentage before redshirt-sophomore Josh Kirson came in, saving three shots on five attempts.“I think both goalies did a good job, we didn’t do a great job in that third quarter, I think we got two guys that are really capable, just like a lot of positions there is competition,” Myers said.No. 15 Ohio State heads to Amherst, Massachusetts to take on UMass at 1 p.m. on Saturday.
Spanish manager Marcelino Garcia Toral believe the UEFA Champions League group for Valencia is difficult but not impossibleSpanish La Liga side Valencia has been drawn into one of the most difficult groups of the 2018-2019 UEFA Champions League.The Spanish team will have to play against Italy’s Juventus, England’s Manchester United and Switzerland’s Young Boys.But Valencia coach Marcelino Garcia Toral believes that while the group is difficult, it is not impossible to qualify to the next round.Quiz: How much do you know about David Villa? Boro Tanchev – September 14, 2019 Time to test your knowledge about Spanish legendary forward David Villa.“It’s a difficult group and we knew that being in the third pot would expose us to risks, but there’s nothing impossible in life and that includes this group,” Marcelino told the official Valencia radio station as quoted by Football Italia.“It’s an attractive group, exciting for us and the fans. We’ll try to go through to the next phase and after six games we’ll see where we are.”“Our hope and ambition are to keep going. I’m certain Juventus and Manchester United will consider Valencia to be a minefield and it’ll be very motivating for us against these opponents,” he added.
Facebook Twitter Google+LinkedInPinterestWhatsAppTRINIDAD & TOBAGO, NOVEMBER 28, 2013- Diplomatic doors have been shut on the Dominican Republic…According to a Caribbean news source, CARICOM has reportedly suspended the DR’s application to CARICOM in light of human rights concerns. Since the recent decision of Dominican courts to cancel the citizenships of generations of those born to Haitian migrants there have been reports of violent break-outs and scrutiny from many quarters on that ruling. CARICOM met Tuesday about the matter; chairing the meeting was Hon Ralph Gonsalves, PM of St Vincent and the Grenadines. Facebook Twitter Google+LinkedInPinterestWhatsApp Related Items:
Facebook0TwitterEmailPrintFriendly分享NEW YORK (AP) — Toys R Us is headed toward shuttering its U.S. operations, jeopardizing the jobs of some 30,000 employees while spelling the end for a chain known to generations of children and parents for its sprawling stores and Geoffrey the giraffe mascot. Brandon said on the recording that the company would be filing liquidation papers and there would be a bankruptcy court hearing Thursday. It wasn’t able to compete with a growing Amazon: The toy seller said in bankruptcy filings that Amazon’s low prices were hard to match. And it said its Babies R Us chain lost customers to the online retailer’s convenient subscription service, which let parents receive diapers and baby formula at their doorstep automatically. Toys R Us blamed its “old technology” for not offering its own subscriptions. Brandon said Toys R Us will try to bundle its Canadian business, with about 200 stores, and find a buyer. The company’s U.S. online store would still be running for the next couple of weeks in case there’s a buyer for it. The chain filed for Chapter 11 bankruptcy protection last fall, saddled with $5 billion in debt that hurt its attempts to compete as shoppers moved to Amazon and huge chains like Walmart. But Toys R U’s biggest albatross was its massive debt load since private-equity firms Bain Capital, KKR & Co. and Vornado Realty Trust took it private in a $6.6 billion leveraged buyout in 2005. The plan had been to take the company public again, but weak sales have prevented that from happening. With such debt levels, Toys R Us did not have the financial flexibility to invest in its business. The company closed its flagship store in Manhattan’s Times Square, a huge tourist destination that featured its own Ferris wheel, about two years ago. “We worked as hard and as long as we could to turn over every rock,” Brandon told employees. He put much of the blame on its woes on the media, saying negative stories about the company’s prospects scared customers and vendors. It pledged then to stay open, but Brandon told employees that it had a “devastating” sales performance during the critical holiday season as nervous customers and vendors shied away. That made its lenders more skittish about investing in the company. In January, it announced plans to close about 180 stores over the next couple of months, leaving it with a little more than 700 stores. “Amazon may pick up the dollars, but won’t deliver the experience needed for a toy retailer to survive and thrive in today’s market,” said Marc Rosenberg, a toy marketing executive. Toys R Us had about 60,000 full-time and part-time employees worldwide last year. The company didn’t do enough to emphasize that it was reorganizing but not going out of business, Silver said. That misperception led customers to its stores because they didn’t think they would be able to return gifts. But the company lost ground to discounters like Target and Walmart, and then to Amazon, as even nostalgic parents sought deals elsewhere. GlobalData Retail estimates that nearly 14 percent of toy sales were made online in 2016, more than double the level five years ago. Toys R Us still has hundreds of stores, and analysts estimate it still sells about 20 percent of the toys bought in the United States. Toys R Us was also hurt by the shift to mobile devices taking up more play time. But steep sales declines over the holidays and thereafter were the deciding factor, said Jim Silver, who is editor-in-chief of toy review site TTPM.com. The closing of the company’s 740 U.S. stores over the coming months will finalize the downfall of the chain that succumbed to heavy debt and relentless trends that undercut its business, from online shopping to mobile games. Now, the $11 billion in sales still happening at Toys R Us each year will disperse to other retailers like Amazon and discounters, analysts say. Other chains, seeing that Toys R Us was vulnerable, got more aggressive. J.C. Penney opened toy sections last fall in all 875 stores. Target and Walmart have been expanding their toy selections. Even Party City is building up its toy offerings. CEO David Brandon told employees Wednesday the company’s plan is to liquidate all of its U.S. stores, according to an audio recording of the meeting obtained by The Associated Press. Toys R Us had dominated the toy store business in the 1980s and early 1990s, when it was one of the first of the “category killers”— a store totally devoted to one thing. Its scale gave it leverage with toy sellers and it disrupted general merchandise stores and mom-and-pop shops. Children sang along with commercials about “the biggest toy store there is.” It’s likely to also liquidate its businesses in Australia, France, Poland, Portugal and Spain, according to the recording. It’s already shuttering its business in the United Kingdom. That would leave it with stores in Canada, central Europe and Japan, where it could find buyers for those assets. The Wayne, New Jersey-based company declined to comment. The company’s troubles have affected toy makers Mattel and Hasbro, which are big suppliers to the chain. But the likely liquidation will have a bigger impact on smaller toy makers, who rely more on the chain for sales. However, many have been trying to diversify in recent months as they worried about the chain’s survival. In filing for bankruptcy protection last fall, Toys R Us pledged to make its stores more interactive. It added demonstrators for the holiday season to show people how toys work, and began opening Play Labs at 42 stores, areas where children can play with different items.
Citation: Researchers use magnets to cause programmed cancer cell deaths (2012, October 8) retrieved 18 August 2019 from https://phys.org/news/2012-10-magnets-cancer-cell-deaths.html More information: A magnetic switch for the control of cell death signalling in in vitro and in vivo systems, Nature Materials (2012) doi:10.1038/nmat3430AbstractThe regulation of cellular activities in a controlled manner is one of the most challenging issues in fields ranging from cell biology to biomedicine. Nanoparticles have the potential of becoming useful tools for controlling cell signalling pathways in a space and time selective fashion. Here, we have developed magnetic nanoparticles that turn on apoptosis cell signalling by using a magnetic field in a remote and non-invasive manner. The magnetic switch consists of zinc-doped iron oxide magnetic nanoparticles5 (Zn0.4Fe2.6O4), conjugated with a targeting antibody for death receptor 4 (DR4) of DLD-1 colon cancer cells. The magnetic switch, in its On mode when a magnetic field is applied to aggregate magnetic nanoparticle-bound DR4s, promotes apoptosis signalling pathways. We have also demonstrated that the magnetic switch is operable at the micrometre scale and that it can be applied in an in vivo system where apoptotic morphological changes of zebrafish are successfully induced. Breast cancer drug pushes colon cancer cells to their death A schematic representation of the magnetic switch for apoptosis signalling in in vitro cells and in a zebrafish. Credit: (c) Nature Materials (2012) doi:10.1038/nmat3430 © 2012 Phys.Org (Phys.org)—A team of researchers in South Korea has developed a method to cause cell death in both living fish and lab bowel cancer cells (in vivo and in vitro) using a magnetic field. The application of the magnetic field, as described in their paper published in the journal Nature Materials, triggers a “death signal” that leads to programmed cell death.
Boys and girls belonging to sexual minority groups such as gay, lesbian and bisexuals are increasingly indulging in disordered eating trends than their heterosexual or straight peers, a new study suggests.Disordered eating behaviour refers to unhealthy eating habits that have not been diagnosed by a physician as an eating disorder, although they are still serious and have the potential to be harmful.In the study which was published in the journal ‘International Journal of Eating Disorders’, the researchers mentioned that the rate of disordered eating behaviours is actually increasing among lesbians and bisexuals, which is alarming. Also Read – ‘Playing Jojo was emotionally exhausting’According to the study, sexual minority peers may also purge or take laxatives, use diet pills or fast to lose weight than their straight peers. The researchers also found that lesbians were twice as likely to report purging and fasting for weight control. Heterosexual boys had the lowest rates of these behaviours and they declined even further over the years. The study, which analysed data from teenagers between the age of 12 to 18, found that there were disparities in disordered eating behaviours which appeared to be declining for straight teenagers. However, the gap between them and sexual minority teenagers remained and for lesbian and bisexual girls, the gap appears to be widening.“While it’s promising to see improvements in the rate of disordered eating behaviours among heterosexual youth, we cannot say there has been any definite reduction of these behaviours for sexual minority youth,” said Ryan Watson, Researcher at the University of British Columbia in Canada.